Science Lesson


It helps to understand the science behind myasthenia. Here is our basic explanation.

Your brain sends electrical waves to your nerves to move the muscles. This sends hundreds of AC h (Acetyl-Choline) antibodies to the nerve endings. Let’s call these keys.

Upon the muscle is the AC h receptor, the lock.

The keys arrive at the lock and switch the muscles into action. Normally, there are more keys than necessary, so the chemical AChe (Acetyl-Choline Esterase) gets rid of the extra keys and the muscle relaxes again. 

In myasthenia an immune attack destroys many of the locks so there are too few to trigger the muscles. Drugs like Mestinon (pyridostigmine) stop the AChe from getting rid of the keys so there is a better chance of them getting to the locks. 

Read our A to Z of myasthenia

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